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Erectile dysfunction risk could be in the genes

It is likely that some cases of erectile dysfunction are caused in part by genetics. But until recently, no single gene had been specifically found for a genetic link with erectile dysfunction.

Now researchers think they may have found a gene that is linked with the risk of erectile function in later life. The SIM1 gene is already known to play a part in sexual function and according to a recent report in the science journal PNAS, it could be linked to erectile dysfunction.

Thousands of DNA codes of men with erectile dysfunction were compared to the DNA codes of men without symptoms. The researchers pinpointed a region of DNA very close to the SIM1 gene where the code was more likely to be different in men with erectile dysfunction.

This discovery may help to understand the cause of erectile dysfunction in some men, and lead to new treatments to treat it.   

Read more in our journal article reviews.

Posted in Erectile dysfunction, Middle-aged and older males, Uncategorized |

Andrology Australia have a new factsheet on pre-conception health for dads-to-be

To coincide with Fertility Week, 15-21 October 2018, Andrology Australia are pleased to present a brand new factsheet for men who are planning to become dads.

Being healthy before trying for a baby is important for both parents, but sometimes the health of the man in the relationship is overlooked. A man’s health and lifestyle can affect the chances of getting his partner pregnant as well as the future health of children who inherit his genes.

Pre-conception health for dads includes five key actions!

Download the new Pre-conception health for dads factsheet

Posted in Fertility, Men's health, Preconception health |

The Healthy Male Newsletter Spring edition is out now!

The Healthy Male, Spring issue


Issue 68 of The Healthy Male newsletter is out now. Among a host of featured topics, this edition highlights Andrology Australia’s partnership in the Fertility Coalition, Your Fertility. Fertility Week, is coming up soon (15-21 October) and Andrology Australia are helping to develop new resources for pre-conception health for dads.

Download The Healthy Male

Continue reading

Posted in Andrology Australia, Newsletter |

Oestrogen therapy and acute cardiovascular events in trans women

Transgender people (whose gender identity differs to their sex assigned at birth) may choose to undergo hormone therapy to align their physical appearance with their gender identity.

For a trans woman (born as a male and identifies as a female) medical transition includes oestrogen therapy. However, there have been concerns about an increased risk of cardiovascular events in trans women who have had oestrogen therapy.

A large study in the US, published in Annals of Internal Medicine, compared the incidence of cardiovascular events in more than 2800 trans women who were treated with oestrogen therapy with matched male and female controls (reference groups).

The results indicate a long-term increased risk of cardiovascular illnesses in trans women receiving oestrogen therapy compared to the reference group, highlighting a need for vigilance among health professionals who care for trans women.

Read more in our journal article reviews.

Posted in Clinical management, Knowledge exchange, Transgender persons |

Using preclinical models to discover new treatments for advanced prostate cancer

Despite many new treatments for advanced (castration-resistant) prostate cancer, this aggressive from of cancer remains incurable. A team of researchers at Monash University, Melbourne have established new preclinical models of advanced prostate cancer that can be studied in the laboratory.

Patient-derived xenografts (PDX) are primary tumours collected from a patient, which are then grown up in the laboratory setting. These tumours can be closely studied and new treatments can be tested prior to taking a drug to clinical trial.

The study, published in European Urology, successfully established a bank of castration-resistant prostate cancer PDX models and then used these models to test a range of drugs to see if they could slow growth of the cancer.

A particular set of drugs that inhibit protein synthesis in the cell were found to reduce tumour growth when used in combination. These exciting findings provide a strong rationale for testing these drugs in patients as part of a clinical trial.

Read more in our journal article reviews.

Posted in Knowledge exchange, Men's health, Middle-aged and older males, Prostate cancer |

Men’s Health Week evaluation time!

Please now take a few minutes to reflect on our resources, from the ‘it’s healthy to talk’ theme through to the design and appeal of our imagery, we would love your feedback.

Please complete our online survey, which only wakes around 5 minutes.  Your response will help ensure the success of future health promotion campaigns.

https://mailchi.mp/e/menshealthweek_evaluation-2018

 

 

Posted in Uncategorized |

Immunotherapy hope for patients with advanced prostate cancer

Immunotherapy is an exciting new weapon in the treatment of aggressive cancers that works by harnessing the body’s own immune system to eradicate cancer cells. In prostate cancer, the success of immunotherapy in clinical trials is mixed. Where many patients show little response to immunotherapy treatments, other patients have outstanding responses, significantly improving life expectancy.

The ability to pre-select which prostate cancer patients are likely to respond to immunotherapy and which patients are unlikely to benefit, would be a major advance in personalising treatments for maximum benefit.

A study, published in Cell, evaluated the genetic identity of hundreds of advanced metastatic prostate cancers to identify a unique subgroup characterised by a defect in the CDK12 gene.

Researchers at the University of Michigan, found that this particular subgroup of prostate cancers have a distinct genetic identity and tumour immune microenvironment that may respond well to immunotherapy. Whilst preliminary, these exciting findings could pave the way to effective personalised treatment for some advanced prostate cancers.

Read more in our journal article reviews.

Posted in Knowledge exchange, Men's health, Middle-aged and older males, Prostate cancer |

The Healthy Male Newsletter Winter edition is out now!

The Healthy Male, Winter issue


Issue 67 of The Healthy Male newsletter is out now. Among a host of featured topics, this edition focusses on male infertility and fertility testing in the clinic, highlighting the need for men to be thoroughly reviewed at the same time as their female partner.

Download The Healthy Male

 

Participate in our study! 

We are seeking participants to complete a 15-20 minute online survey examining the ways that men prefer to seek out health information. If you are male (18+) and would like to take part, please go to our online survey. Your help is appreciated and will help steer how health information is provided to men in the future.

Continue reading

Posted in Andrology Australia, Newsletter |

Andrology Australia has recently updated 20 fact sheets

Andrology Australia has a catalogue of fact sheets on a wide range of male health topics. We have recently released 20 updated fact sheets with more on their way!

Here’s a preview:

Erectile dysfunction

Erectle dysfunction fact sheet

Erectile dysfunction (when a man is unable to get and/or keep an erection) is very common and becomes more common as men age. An Australian survey showed that at least one in five men over the age of 40 years has erectile problems and about one in ten men are completely unable to have erections. 

Read the information online or download the PDF fact sheet.

Physical activity and men’s health

TN-Factsheet_PhysicalActivity

Men suffer from high rates of cardiovascular disease; coronary heart disease is the leading cause of death in Australian men. Preventing cardiovascular disease and diabetes, and addressing common risk factors (smoking, high blood pressure, high cholesterol, being overweight) is therefore particularly important for men.

Read the information online or download the PDF fact sheet.

Penis problems

Penis problems fact sheet

 

This fact sheets looks at different penis problems that men may encounter, including penis lumps, penis cancer (rare), penis injury and persistent erections (priapism).

Read the information online or download the PDF fact sheet.

Androgen deprivation therapy

Androgen deprivation therapy fact sheet

Androgen deprivation therapy (ADT) is a treatment that works well for many men with prostate cancer. ADT does not cure prostate cancer but it may help to keep the growth and progression of the disease ‘in check’ for a period of time.

Read the information online or download the PDF fact sheet.

Posted in Erectile dysfunction, Men's health, Prostate cancer, Reproductive health, Sexual health | Tagged , , , ,

The SHAPE project is looking for participants 60 years and over

Sexual health is an important component of health and wellbeing and sexual activity enhances physical and mental health during ageing. The Sexual Health & Ageing, Perspectives and Education (SHAPE) Project, presents a unique opportunity for older adults to voice their thoughts and provide guidance to researchers in the development of a unique sexual health discussion checklist for use in primary care.  
While discussion of sexual health is a core preventive health activity in general practice for young adults, it is seldom discussed between healthcare practitioners and their older patients. Research has identified barriers to these discussions occurring, including lack of training, insufficient knowledge about older adults’ sexual health needs, and assumptions that older patients have little interest in sexual activity. Research has found that while embarrassed to initiate sexual health discussions with healthcare practitioners, older people want to be asked and to have opportunities to discuss their concerns.

For further details click here to view the Project flyer.

 

Posted in Community health, Research and Evaluation, Training and Education |
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